One of These Algae is Spirogyra sp : A Part from the Book Chapter : Understanding the Effect of Bioactive Compounds from Spirogyra sp. in Reducing the Protoscolices Viability In-vitro compared with Albendazole Drug

Spirogyra

Several algae species, which can be of a very high nature, have been used for new sales of biological activity, including micro-algae, which are important in medical and commercial terms for containing high-value active materials and processing molecules. Disease may act as antibiotics for a large number of microorganisms including parasites, being able to produce a wide range of active biochemical compounds, immunosuppressants, cytotoxic and enzyme inhibitors.

Most of the components isolated from algae or plants belong to the group of phenols, tannins, peptides, Saponins, triterpenes, and alkaloids. One of these algae is Spirogyra sp. a rich source of natural chemicals that can be derived from simple methods.

The present study extracted medical material contained in Spirogyra Sp.by Gas Chromatography-Mass Spectrometry (GC/MS). A statement of the effect of the extract in reducing the viability of the protoscolices of the parasite Echinococcus granulosus has been compared with the albendazole drug in vitro.

Author(s) Details:

Hadi M. Almayali
Biology Determent, Faculty of Education, University of AL-Qadisiyah, Al-Dewania, Iraq.

Haider M. Alkaabi
Biology Determent, Faculty of Education, University of AL-Qadisiyah, Al-Dewania, Iraq.


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Recent Global Research Developments in Effects of Bioactive Compounds from Spirogyra sp.

Cultivation of Spirogyra in Photobioreactors:

  • A study investigated the growth kinetics of Spirogyra sp. in a flat-panel airlift photobioreactor. The algae required high photon-flux densities (up to 1400 µmol m⁻² s⁻¹) for maximum proliferation, achieving a maximum volumetric productivity of 1.15 g DW L⁻¹ day⁻¹ and a final biomass concentration of 14.28 g DW L⁻¹ [1.]
  • This research sheds light on large-scale cultivation methods for Spirogyra, which could be valuable for biotechnological applications.

Bioactive Compounds from Spirogyra:

  • Spirogyra spp. is consumed as food in many Asian countries and is a valuable source of natural bioactive compounds.
  • These compounds exhibit antibiotic, antiviral, antioxidant, anti-inflammatory, and cytotoxic activities [2].
  • While specific bioactive compounds were not mentioned in the provided research, Spirogyra’s potential warrants further exploration.

Anti-Biofilm Activity:

  • Marine algae, including Spirogyra, are promising sources of novel compounds with anti-biofilm activity [3].
  • Biofilm inhibition is crucial for various applications, including healthcare and environmental protection.

References

  1. Vogel, V., Bergmann, P. Culture of Spirogyra sp. in a flat-panel airlift photobioreactor. 3 Biotech 8, 6 (2018). https://doi.org/10.1007/s13205-017-1026-9
  2. Kumar J, Dhar P, Tayade AB, Gupta D, Chaurasia OP, Upreti DK, et al. (2015) Chemical Composition and Biological Activities of Trans-Himalayan Alga Spirogyra porticalis (Muell.) Cleve. PLoS ONE 10(2): e0118255. https://doi.org/10.1371/journal.pone.0118255
  3. Behzadnia A, Moosavi-Nasab M and Oliyaei N (2024) Anti-biofilm activity of marine algae-derived bioactive compounds. Front. Microbiol. 15:1270174. doi: 10.3389/fmicb.2024.1270174

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